ALS Highlights the Mechanism of DNA Synthesis Publication

The Advanced Light Source at the Berkeley Lab highlights the Chaput lab’s recent publication on the mechanism of DNA synthesis in a Science Brief. The specific Nature Communication publication discusses newly discovered intermediates that provide greater context to replication by a DNA polymerase; the exact order and transition between intermediates was solved by time-resolved X-ray…

Read More

“Expanding the Chemical Diversity of TNA with tUTP Derivatives that are Substrates for a TNA Polymerase” Manuscript Accepted

The TNA UTP base analog manuscript, entitled “Expanding the Chemical Diversity of TNA with tUTP Derivatives that are Substrates for a TNA Polymerase”, has just been accepted into Chemical Communication! 

Read More